Which nervous system directs skeletal muscles to respond in the body's fight-or-flight response?

The nervous system that directs skeletal muscles to respond in the body's fight-or-flight response is the sympathetic nervous system. During stressful situations, the sympathetic division activates a series of physiological changes designed to prepare the body for rapid action. This includes increasing heart rate, redirecting blood flow to muscles, and releasing adrenaline, which enhances muscle strength and energy.

In the context of the fight-or-flight response, the sympathetic nervous system plays a crucial role by stimulating skeletal muscles to prepare for quick movements, whether to flee from danger or confront it. This preparedness is essential for survival and allows the body to function effectively under acute stress.

Other systems, such as the parasympathetic nervous system, work to maintain homeostasis and conserve energy during non-stressful times and would not be responsible for initiating the fight-or-flight response. The central nervous system, comprising the brain and spinal cord, processes sensory information and coordinates responses but does not directly activate the muscles in the context of immediate fight-or-flight situations. The enteric nervous system primarily governs the gastrointestinal system and is not involved in skeletal muscle response to stress.