What is best studied using an electron microscope?

The best subject to study using an electron microscope is the structure of cellular organelles. Electron microscopes have the capability to achieve much higher resolutions than light microscopes, allowing scientists to visualize structures at the cellular level with great detail. This includes the various organelles such as mitochondria, endoplasmic reticulum, and Golgi apparatus, which are crucial for understanding cell function and organization.

The power of an electron microscope comes from its use of electron beams instead of light, which permits the examination of specimens at a much smaller scale. This level of detail is essential for studying the intricate structures and functions of organelles, which can be critical for research in cellular biology, medical diagnostics, and various scientific applications.

In contrast, the other options involve structures that either require different types of imaging techniques or are at scales that might be less relevant for electron microscopy. Studying atoms or chemical bonds often requires approaches such as atomic force microscopy or other specialized forms of spectroscopy. Skeletal joints are larger structures that do not necessitate the high magnification and detail provided by an electron microscope, as they can be effectively studied using traditional imaging methods like X-rays or MRIs.